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Cochrane Review: Point of Care CRP testing can safely reduce antibiotic prescribing in primary care

Antibiotic resistance has become a major public health problem, with some infections no longer treatable using currently available drugs.

The inappropriate use of antibiotics is associated with the increase of resistance. Most antibiotics are prescribed in primary care, and most commonly for Acute Respiratory Infections (ARIs). In most cases ARIs seen in primary care are spontaneously resolved without antibiotics. The management of ARIs in primary care is therefore a key target for influencing the antibiotic prescribing behaviour of clinicians.

A new Cochrane Overview has identified effective and safe clinician-focussed interventions to reduce antibiotic prescribing for acute respiratory infections (ARIs) in primary care.

The authors concluded that point of care CRP testing reduces antibiotic prescribing for patients with ARIs in primary care with no negative effects on the outcomes of patient satisfaction and re-consultation.

Check out how the fully automated Alere Afinion™ CRP test can help guide treatment decisions with excellent precision and user friendliness in 4 minutes.

Read our case study on the use of CRP testing

Read the full Cochrane Review

 

Official Statement regarding Support
Biolog 3000i & 12 Lead Patient Cable ECG System:

In January 2014, Numed announced that the Biolog 3000i ECG System was approaching its end of life due to a shortage of spare parts being available.
We realise and appreciate that the Biolog ECG System is still unique, and have extended the support on these units as much as possible. Numed Healthcare have also provided some alternative products with special pricing for MediServe customers wanting to trade in their old Biolog ECG System.
We have just managed to source an alternative manufacturer for some spare parts that were in constraint, allowing us to give more time for customers to trade in their current Biolog ECG System when funds allow.
However, Numed now has a definitive “End of Life” road map for the Biolog ECG System:
• Biolog 3000i ECG Systems covered by support contracts will be supported until the 30th September 2018
• New twelve month MediServe Contracts will be issued up until 30th September 2017
• From 1st October 2017, all remaining spares will be reserved for those Biolog ECG Systems on support contracts.
• There will be no increase in the annual support costs for MediServe in the interim period.
This provides a definitive cut-off date for support and supply of spare parts for this ECG

ANGLE plc (“the Company”)

RESEARCHERS DEVELOP PARSORTIXTM-BASED PROCESS TO EFFICIENTLY HARVEST CANCER CELLS FROM BONE MARROW

Reactivation of such dormant cells has been implicated in patients with cancer relapse.

 ANGLE plc (AIM:AGL OTCQX:ANPCY), a world-leading liquid biopsy company, today announces that the Center for Women’s Health Tuebingen, Germany, has presented the first report on a successful establishment of a protocol for detecting disseminated tumour cells (DTCs) using cancer patient bone marrow with the ParsortixTM system.

The reactivation of dormant DTCs and their release into the bloodstream as circulating tumour cells (CTCs), is the process by which a patient may, sometimes after many years of remission, suffer a relapse through metastasis. There is intense interest in the existence and status of such DTCs that are “hibernating” in the bone marrow.

 At present, the method of choice for detecting DTCs is a density gradient centrifugation of the bone marrow to enrich for mononuclear cells and then an antibody-based staining for various cell markers.  In experiments with spiked cancer cells this procedure was shown to be accompanied by a tremendous reduction of target cells with an average of up to 80% cell loss. This may well be one reason why, in primary breast cancer, DTCs have been found in the bone marrow of only 20-30% of patients.

 The Tuebingen researchers have shown that their newly established ParsortixTM based protocol allows a recovery of about 80% of input target cells. Furthermore, the Tuebingen team believe that this easy to use method may well be applicable to other (non-blood) body fluids for detection of tumor cells for liquid biopsies.

 The University Hospital Tuebingen research results were presented in a poster at Europe’s leading CTC conference, the Third International Advances in Circulating Tumour Cells (ACTC) Symposium. A copy of the poster is available at https://angleplc.com/library/publications/.  

 

ANGLE Founder and Chief Executive, Andrew Newland, commented:

“The presence of disseminated tumour cells (DTCs) in bone marrow has been shown in multiple studies to be predictive of clinical relapse. The research from the Center for Women’s Health in Tuebingen demonstrates the utility of ParsortixTM in harvesting disseminated cancer cells from bone marrow, extending the potential applications of our liquid biopsy system significantly.”

 

Dr. André Koch, Center for Women’s Health, Tuebingen commented:

“The ParsortixTM system shows huge promise in improving the efficiency of isolating DTCs from bone marrow. At our Women’s Hospital, taking bone marrow is routine during surgery on breast cancer patients, so improvements to processing and then analysis of the bone marrow are particularly valuable. We are excited about the opportunities this opens up.”

All cultures throughout history have used the healing effects of herbs to help treat health problems. Today, we are experiencing a resurgence in the practice of herbal medicine.

The herbs we are turning to in our quest to heal ourselves, reduce or eliminate chemicals from our bodies are the same ones that were used in ancient practices from China, India, and Egypt, where written documents of herbal medicines date back to 5,000 years.

Herbal medicine takes on many remedy forms:​

  • Teas and bath additives, using fresh or dried herbs and are mixed in water.
  • Tinctures which contain plant extracts added to alcohol or glycerin.
  • Essential oils are distilled from plant materials.
  • Liniments and salves that are applied to the skin contain dried herbs.
  • Powders and pills contain dried extracts.

Herbal medicine is very useful for self treating mild symptoms and chronic complaints. It is also very effective for preventing illnesses by strengthening the immune system to stimulate the body’s own healing abilities.

Have you tried Apple Cider Vinegar For Blood Pressure Fluctuation?​

High blood pressure is a one condition that affects many people regardless of shape and size, age, and social class. High blood pressure is often left untreated and uncontrolled because its symptoms are difficult to recognize.

If left untreated, the walls of the blood vessels can harden, resulting in a heart attack or stroke. Constricted blood vessels cause increased resistance to the blood flow and causes the blood pressure to rise.​

​How To

There are natural remedies that can help with dealing with high blood pressure, many of which are in herbal form.​ We’re going to break it down into three simple ways you can make your own high blood pressure remedy at home.

Teas​

Learn how to use Baking Soda For Heartburn Treatment​

Help strengthen the heart muscle and keep the blood pressure level. To improve cardiac function make a mix of equal parts Hawthorn flowers, blueberry leaves, shepherds purse, Hibiscus, parsley, skullcap, or alfalfa. Add to boiling water, steep for around 10 minutes then strain. Drink twice a day.

To increase circulation and help dilate the blood vessels, make a tea using dried yarrow flowers. Drink 3 times a day for maximum benefits.

Pills And Powders

​If you’re looking for some relaxing herbs, try passion flower, or California poppy root. These plants helps reduce the stress that can raise the blood pressure. You can find them in pill form, but first consult your doctor whether or not they are good for you.

However, if you’re looking for something in more of a supplement form, go for Ginkgo, ginger, garlic. They are all known to prevent hardening of the arteries and reduces blood pressure.​

Check here our top home remedies for swollen feet

Tinctures​

Tinctures are most effective due to the alcohol which draws the active compounds in the herb and absorbs faster into the bloodstream. Black cohosh, Blue cohosh, or Wild Cherry are all recommended to prevent high blood pressure. Just add 7-10 drops into a water, or any hot beverage. Drink 2-3 times daily.​

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